AABB 2015


The 2015 AABB Annual Meeting took place October 22-27 in Anaheim, California.


Timing of irradiation affects RCCs

Jen Smith Read Article
Published: 11/11/15

Red cells for transfusion

The timing of gamma irradiation influences in vitro characteristics of red cell concentrates (RCCs), according to a new study. The research showed that RCCs sustain more damage the longer they are stored prior to gamma irradiation and the longer they are stored after irradiation. However, RCCs from female donors appeared to be less susceptible to irradiation injury, and the additive solution used seemed to affect the level of injury as well. [Read Article]

Newer apheresis system appears superior to standard

Jen Smith Read Article
Published: 11/06/15

Apheresis donation
Photo by ec-jpr

A newer, more streamlined apheresis system yields more CD34+ cells from stem cell transplant donors than a previous system, according to a new study. Researchers used both tools—the COBE Spectra Apheresis System and the Spectra Optia Apheresis System—to collect mononuclear cells (MNCs) from healthy donors and found the collection efficiency and yield was superior with the Spectra Optia.  [Read Article]

Survey: 3 in 10 MSMs don’t comply with UK blood donor policy

Jen Smith Read Article
Published: 11/04/15

Blood donation
Photo by Marja Helander

A survey of UK blood donors suggests that as many as 30% of donors who are men who have sex with men (MSM) may not be compliant with the MSM blood donor policy. The UK’s policy requires that MSMs do not donate blood if they have engaged in sexual activity with another male in the last 12 months. But the survey indicates that as many as 3 in 10 MSMs are disregarding this policy. The research also suggests that MSMs who do not comply . . . [Read Article]

Interventions can treat, prevent iron deficiency in blood donors

Jen Smith Read Article
Published: 11/03/15

Blood donation in progress

Data from the STRIDE study have revealed interventions that can mitigate iron deficiency in repeat blood donors. The study showed that providing repeat blood donors with iron supplements significantly improved their iron status. But informing donors about their ferritin levels and recommending they take iron pills also significantly improved their iron status. Meanwhile, patients in control groups became more iron-deficient over the study period. [Read Article]

Assay can detect and classify DOACs

Jen Smith Read Article
Published: 11/02/15

blood_sample_collection_Juan_D_ Alfonso_230.jpg
Blood sample collection
Photo by Juan D. Alfonso

A new assay can detect and classify direct oral anticoagulants (DOACs) quickly and effectively, according to researchers. In tests, the assay detected DOACs with greater than 90% sensitivity and specificity. The assay classified the direct thrombin inhibitor (DTI) dabigatran correctly 100% of the time and classified factor Xa inhibitors (anti-Xa), which included rivaroxaban and apixaban, correctly 92% of the time. [Read Article]

Blood donors’ genetic background affects hemolysis

Jen Smith Read Article
Published: 10/31/15

Red blood cells

Interim results of a large study suggest a blood donor’s genetic background and frequency of donation influence red blood cell (RBC) storage and stress hemolysis. Investigators found that donor ethnicity and gender both affected hemolysis, but the effects sometimes differed between storage and stress hemolysis. Similarly, RBCs from frequent donors were more susceptible to storage and osmotic hemolysis but less susceptible to oxidative hemolysis. [Read Article]

Canada may shorten deferral for MSM blood donors

Jen Smith Read Article
Published: 10/30/15

Blood donation
Photo by Charles Haymond

Lifting the lifetime ban on blood donations from men who have sex with men (MSM) has not altered the safety of the blood supply in Canada, according to a new study. The study showed no increase in the rate of HIV-positive blood donations since Canada changed its policy regarding MSM blood donors, allowing MSM to donate if they have not had sexual contact with another man in the last 5 years. Because of this finding, Canada may shorten the deferral period . . .  [Read Article]


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