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Pediatric Hematology

Proximity to oil, gas wells linked to ALL

HT Staff Read Article
Published: 02/16/17

A pumpjack in west Texas.
A pumpjack is used to lift
liquid from an oil well.
Photo by Eric Kounce

Living in an area of high-density oil and gas development may increase a young person’s risk of developing acute lymphoblastic leukemia (ALL), according to research published in PLOS ONE. The study showed that children and young adults in Colorado who had been diagnosed with ALL were more likely than young people with non-hematologic cancers to live in areas of high-density oil and gas development. [Read Article]

Study reveals patterns of ED use in SCD patients

HT Staff Read Article
Published: 02/15/17

Doctor examines SCD patient
Photo courtesy of St. Jude
Children’s Research Hospital

Population-based surveillance data has revealed patterns of emergency department (ED) visits among Californians with sickle cell disease (SCD). Previous research suggested that between one-half and two-thirds of SCD patients’ ED visits end in a discharge from the ED, called a treat-and-release visit. The remainder result in admission to a hospital or other treatment facility. The purpose of the current study was to use data from the . . . [Read Article]

G-CSF could prevent infertility in cancer patients

HT Staff Read Article
Published: 02/14/17

Lab mouse

Granulocyte colony-stimulating factor (G-CSF) could prevent infertility in male cancer patients, according to preclinical research published in Reproductive Biology and Endocrinology. Researchers said they found that G-CSF protects spermatogenesis after alkylating chemotherapy by stimulating the proliferation of surviving spermatogonia. The team also found evidence to suggest that G-CSF may be useful as a fertility-restoring treatment. [Read Article]

Childhood cancer treatment linked to psychosexual development

HT Staff Read Article
Published: 02/06/17

Child with cancer
Photo by Bill Branson

Researchers say the intensity of neurotoxic treatment given to children with cancer may be an indicator of their risk for psychosexual impairment in adult life. The researchers compared adults who survived childhood cancer to matched control subjects and found that, overall, the 2 groups reported similar sexual and romantic experiences. However, cancer survivors who received high-dose neurotoxic treatment had inferior psychosexual development. [Read Article]

Therapy demonstrates safety, efficacy in kids with hemophilia B

HT Staff Read Article
Published: 02/06/17

Eftrenonacog alfa
Photo courtesy of Biogen

Eftrenonacog alfa, a recombinant factor IX Fc fusion protein, has produced favorable results in children with severe hemophilia B, researchers have reported. The team said eftrenonacog alfa was generally well-tolerated in the phase 3 Kids B-LONG study, and none of the patients on this trial developed inhibitors. In addition, the annualized bleeding rate was low, and most patients were able to maintain once-weekly dosing. [Read Article]



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